~ Current Funding Opportunity ~
Maine Medical Center (MMC) provides intramural clincial and translational research grants to its employed and affiliated faculty, staff, and trainees through resources made available to the Maine Medical Center Research Institute (MMCRI) and the MMC Neuroscience Institute (NSI).
The grant application deadline is SEPTEMBER 10, 2012.
Other Research Projects
MMC is one of four sites in New England participating in a Phase III/Pivotal trial for patients with newly diagnosed glioblastoma multiforme (GBM). The NovoCure multi-center trial prospectively compares patients treated with the Novo TTF-100A with temozolomide to patients treated with temozolomide alone. The treatment is based on non-invasive, chronic applications of alternating electric fields to the tumor site using insulated surface electrodes. Results from in vitro and pilot studies have demonstrated prolonged time to disease progression and extension of survival. Rajiv Desai, MD, of MMP-Neurosurgery & Spine, is the Principle Investigator on this trial. Novocure Trial Information
MMC has been accepted to participate in an industry sponsored multi-center, Phase 3b trial (ACCELERATE) to evaluate clevidipine as an acute antihypertensive agent in Acute Cerebral Hemorrhage. Richard Riker, MD, Critical Care Medicine, has received funding by the Neuroscience Institute to support this research study.
Eric Dinnerstein, MD, a cognitive neurologist at Maine Medical Partners Neurology, is the principal investigator of a multicenter Phase 3 trial regarding the use of a monoclonal antibody Bapineuzumab as a potentially disease modifying agent for dementia of the Alzheimer's type. MMP Neurology is the only site in Maine conducting this trial, and one of only a handful of sites in the northern New England region.
Heidi Henninger, MD, of Maine Neurology, is the Prinicipal Investigator for the following two clinical trials.
Project Title: Good Grade Sub-Arachnoid Hemorrhage Routinely Treated In a Neuro-Stepdown Unit
Project Title: Maine Cool- A Regional Collaborative Therapeutic Hypothermia Project
Project Title: Identification of Chemo-radiation Resistant Stem Cells in Recurrent Glioblastoma Multiforme
Project Title: Effect of Induced Hypertension on Cerebral Oxygen Utilization in Encephalopathic Survivors of Cardiac Arrest
Project Title: Cthrc1, A Possible Diagnostic Marker of Neural Tumor Progression and Vascularization
Project Title: Proteomic Characterization of Cerebrospinal Fluid (CSF) in Patients with Lyme Meningitis by High Resolution LC-Mass Spectrometry (MS/MS)
Project Title: Predictors of Return to Work in Worker's Compensation Patients Following Spine Surgery
Project Title: Creation of MMC Carotid Tissue Bank
Project Title: Therapeutic Hypothermia Research Group
Project Title: Objective CT Assessment of Hydrocephalus
Project Title: Assessing the Accuracy and Inter-Rater Reliability of Bedside Optic Nerve Sonography in Healthy Volunteers